Sugammadex in a patient with Sjogren's syndrome and polymyositis.
نویسندگان
چکیده
understood entity resulting from CSF leakage or from venous hypotension causing increased CSF absorption. It causes a range of symptoms from orthostatic headaches to coma. MRI and CT myelography are the investigations of choice in demonstrating CSF leaks as presumed sites of dural defects. CT myelography has traditionally been the first diagnostic tool, but this necessitates lumbar puncture for contrast injection and this is both invasive and of significant riskwith infra-tentorialherniation. MR myelography has been shown to have comparable detection rates in nerve root leaks and high cervical retrospinal CSF collections, and superior detection rates in spinal leaks. A diagnostic quandary arose in this patient who had serious contraindications to MRI and CT myelography. The presence of a PPM is widely recognized as a contraindication to MRI due to the risk of harmful arrhythmias and heating or displacement of the device or its leads. In a survey asking radiologists and cardiologists whether they would submit a patient to MRI with a PPM in situ, 97% radiologists responded that they would not, whereas 34% of cardiologists responded that they would under appropriate circumstances. There is now a substantial evidence base providing safety data on a large number of MRI studies with PPMs. The devices for which there is most evidence include those manufactured after 1998, in place for over 6 weeks and without epicardial or abandoned leads. – 7 The number of PPMs will continue to increase due to an ageing population and increasing indications. However, the number of patients with an expanding range of co-morbidities that will benefit from the diagnostic advantages offered by MRI will also multiply. MRI should only be considered when there is no lower-risk alternative to answer clinical questions essential to patient management. This case highlights the commonly overlooked pathology of SIH and raises awareness of the increasing evidence that PPMs are becoming relative rather than absolute contraindications to MRI.
منابع مشابه
Mixed connective tissue disease presenting myasthenia gravis.
We herein describe a 41-year-old female patient with an association of myasthenia gravis (MG) with anti-acetylcholine receptor (AcR) antibody, mixed connective tissue disease (MCTD) and Sjögren's syndrome (SjS). We reviewed the reported association of MG and MCTD, systemic lupus erythematosus, progressive systemic sclerosis, polymyositis and dermatomyositis, and SjS. Since we could find only tw...
متن کاملPolymyositis and Sjögren's syndrome associated with bronchiolitis obliterans organizing pneumonia.
Bronchiolitis obliterans organizing pneumonia (BOOP) occurred in a 53-year-old woman with well-documented Sjögren's syndrome (SjS) and polymyositis (PM). BOOP has often been reported as a pulmonary manifestation of collagen vascular diseases, mainly rheumatoid arthritis (RA), but the association of BOOP and PM has rarely been documented. A search of the literature showed only 16 case reports of...
متن کاملمعرفی یک مورد سندرم نفریت اینترستیشیال حاد و یووئیتیس
Concurrence of interstitial nephritis and uveitis named tubulointestitioal nephritis and uveitis syndrome (TINU) are unusual and uncommon presentations of interstitial nephritis. This syndrome is considered after ruling out other differential diagnoses. A-38-year old man presented with acute renal failure and uveitis. The histologic findings of renal biopsy showed acute tubulointestitioal nephr...
متن کاملAnti-Ku autoantibodies: series of 5 cases.
Autoantibodies directed against nuclear protein Ku are infrequently detected. If present, they are found in high titers in patients with connective tissue overlap syndromes. This article describes 5 patients with anti-Ku antibodies in whom systemic lupus erythematosus, Sjögren's syndrome, idiopathic lung fibrosis or scleroderma - polymyositis overlap syndrome were diagnosed. Interestingly, sign...
متن کاملAutoantibody to NA14 is an independent marker primarily for Sjogren's syndrome.
Nuclear Autoantigen of 14 kDa (NA14) was originally identified using the serum of a Sjögren's syndrome (SS) patient as probe in screening a human testis cDNA expression library. To date there is no report in the systematic analysis of the prevalence of autoantibodies to NA14. In this study, anti-NA14 was determined in several rheumatic diseases from independent cohorts in the US and Japan. The ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- British journal of anaesthesia
دوره 111 6 شماره
صفحات -
تاریخ انتشار 2013